So You Want to Use Retinol? Here Are 5 That Derms Love — and You Can Buy Them on Amazon

Most skincare experts would agree that retinol is the gold standard in anti-aging and delivers a smoother, clearer complexion. A number of studies confirm that retinoids not only boost collagen production — which, in turn, helps firm up skin and smooth out wrinkles — but can also increase cell turnover. As a result, the vitamin A derivative can make skin look brighter and more even-toned.

As much as retinoids are considered miracle workers, they can take some getting used to. Dermatologists suggest incorporating them into your routine slowly — either every other night or once every third night — and taking note of how your skin reacts. If your skin tolerates incremental applications after two weeks, consider gradually increasing to nightly use. Giving your skin time to adjust will help you avoid skin irritation including dryness, redness, flakiness, and sensitivity to the sun.

EDITOR’S NOTE: Retinol shouldn’t be used by women who are pregnant, considering getting pregnant, or nursing. Please consult with your doctor before use.
While discussing your options with a dermatologists is important, you can purchase a slew of retinol-infused products without a prescription from the doc. Amazon is one such purveyor of retinol-infused skincare. We asked dermatologists to divulge a few of the formulas that are worth adding to your next Prime order.

Replenix® All-Trans Retinol Smoothing Serum

Replenix All-trans-Retinol Smoothing Face Serum 5X for Wrinkles, Fine Lines, with Retinol, Green Tea, and Caffeine, 1 Oz
  • This time-released, moisturizing therapeutic serum helps to minimize visible signs of aging and achieve smoother, firmer, more evenly toned skin
  • Retinol-based (0.5%) and enriched with caffeine, this serum boosts radiance and neutralizes free radicals with 90% green tea polyphenols

Similar to how you should gradually work retinol into your routine, you may want to start off with a low dose formula. Dr. Panta Rouhani Schaffer of Gramercy Park Dermatologysm recommends the low-strength formula Replenix® All-Trans Retinol Smoothing Serum so highly, she keeps it stocked in her office. It can tackle multiple signs of aging and enlarged pores with less risk of irritating the skin.

For more advanced signs of aging, including sagging and wrinkles, the brand also makes a medium strength formula and and high-strength formulas, which rely on higher concentrations of retinol.

Medium-strength retinoids work to even out tone and texture, firm up slightly sagging skin, and iron out deep wrinkles while higher strength options can expedite results further. And the brand’s range makes it easy to step up your game if and when you need to. “Replenix has a step-wise approach a patient can take by starting with 2x and eventually building up their skin tolerance to 5x and then 10x,” she says.

SkinMedica Retinol 0.5 Complex

Our experience with SkinMedica Retinol 0.5 Complex has been considerably positive. We’ve noted significant enhancements in skin tone, texture, and resiliency. The fine lines and coarse wrinkles, in particular, have visibly diminished. We believe the encapsulated PhytoShield Complex, an innovative antioxidant technology, has played a crucial role in these improvements, while additionally minimizing any irritation typically associated with retinol.

However, we need to underscore the importance of the cautionary advice. We experienced mild redness, peeling, and irritation, which are expected side-effects with this product. We strongly recommend the use of a sunscreen and limited sun exposure while using this product and for a week following discontinuation. And remember, individuals who are pregnant, lactating, or planning to become pregnant should refrain from using the Retinol Complex.

Deep Wrinkle Anti-Aging Retinol Night Cream

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RoC Retinol Correxion Deep Wrinkle Anti-Aging Night Cream, Daily Face Moisturizer with Shea Butter, Glycolic Acid and Squalane, Skin Care Treatment, 1 Ounces (Packaging May Vary)
  • DEEP WRINKLE NIGHT CREAM: This anti-aging hydrating cream with glycerin works through the night when skin is believed to be most receptive. Wake up to revitalized skin for a smoother, more radiant appearance.
  • FOR DAILY USE: Powered by Retinol & our exclusive mineral complex, this non-greasy, non-comedogenic formula helps reduce the appearance of deep wrinkles by up to 50% while lifting & firming skin*. Made for dramatic results but gentle enough for daily use by men and women.

ROC® is one of the most salient drugstore skincare brands, thanks in part to its retinols, which come in a variety of vehicles suited for various skin types, Dr. Maryann Mikhail of Spring Street Dermatology in New York City explains. Perhaps the most well-known is the brand’s Deep Wrinkle Anti-Aging Retinol Night Cream.

Dr. Debra Jaliman, Assistant Professor of Dermatology in the Icahn School of Medicine at Mount Sinai, loves that it not only delivers the vitamin A-derived active, but it also contains nourishing ingredients like shea butter and squalane. “This cream not only has retinol but also shea butter and squalane, which hydrate and aid in preventing skin aging.”

Neocutis Nouvelle + Retinol Correction Cream

Neocutis Nouvelle+ Retinol Correction Cream - Anti-Wrinkle and Dark Spots - 30mL
  • Country Of Origin: United States
  • Item Package Dimension: 1.6" L x 1.6" W x 6.0" H

Whether they’re caused by scarring, UV rays, or hormone changes, dark spots and other sun damage can stand in the way of an even skin tone and make our skin appear much older than it actually is. According to Rouhani Schaffer, a few dabs of the Neocutis® Nouvelle +® Retinol Correction Cream at night can help fade hyperpigmentation. It also eliminates other signs of aging.

“Nouvelle has extra brightening [ingredients] — it’s really helpful for those with uneven pigmentation,” she says, pointing to the brand’s proprietary Melaplex® technology that works alongside the retinol to deliver a radiant complexion.

StriVectin Advanced Retinol Intensive Moisturizer

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StriVectin Advanced Retinol Intensive Night Moisturizer, Targets Visible Signs of Aging for Healthier Skin, 1.7 Fl Oz
  • Formulated with NIA-114 is our patented, optimized form of Niacin/VitaminB3 clinically proven to strengthen the skin barrier and supercharge the performance of other ingredients for visibly transformed, healthy-looking skin.
  • Visibly smooth & soften the look of fine lines and wrinkles

The StriVectin® Advanced Retinol Intensive Moisturizer is worth its hefty price tag, recommends Jaliman. In addition to retinol, the cream is spiked with a bevy of skin-supporting ingredients, including olive oil, lactic acid, shea butter, aloe, hyaluronic acid, panthenol, and resveratrol; the lattermost, she notes, thwarts skin-aging free radicals — making it the perfect anti-aging partner for retinol.

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